Rapid developments in biologic science are changing how spine fusion procedures are performed, and NanoFUSE Biologics is at the forefront of this progress. Designed as the world’s only FDA-cleared bioactive glass combined with demineralized bone matrix (DBM), NanoFUSE represents a new standard for bone healing and fusion support in spinal surgery.

What Is NanoFUSE?

NanoFUSE is a unique composite graft material that harnesses two well-established processes in bone healing. DBM is widely used for its osteoinductive properties—helping stimulate new bone growth—while bioactive glass is appreciated for its ability to create an optimal environment for bone regeneration (osteostimulation). By combining these attributes, NanoFUSE intends to offer a more consistent and effective pathway to successful spine fusion.

Clinical Application and Versatility

NanoFUSE is available as putty and strips, making it adaptable for surgeons addressing a variety of fusion scenarios, from placing grafts in interbody cages to posterolateral gutters and even complex deformity repairs. This versatility enables clinicians to select the optimal format for each patient and surgical approach, while aiming for reliable graft handling and placement.

Why NanoFUSE stands apart?

Spine surgeons are consistently seeking biologic solutions that combine predictable performance with improved safety. NanoFUSE’s use of synthetic bioactive glass, rather than donor-derived tissue, reduces patient exposure to donor variability and possible transmission risks. The dual action of DBM and bioactive glass also has demonstrated, in preclinical animal studies, enhanced bone formation when compared to either material used on its own.

• Enhanced Environment for Bone Growth: The synergistic relationship of DBM and bioactive glass is designed to maximize the biologic potential for regeneration.

• Safer, More Consistent Outcomes: Reducing reliance on donor tissue moves toward standardized graft performance.

• Multiple Surgical Configurations: Putty and strip options allow easy adaptation for various spine fusion techniques.

Staying updated on innovations such as NanoFUSE Biologics can help clinicians refine their surgical strategies, adapt to shifting standards of care, and realize better patient outcomes.